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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL1
All Species:
10.91
Human Site:
S62
Identified Species:
16
UniProt:
Q9UBP6
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBP6
NP_005362.3
276
31471
S62
A
P
L
T
Q
N
Q
S
H
D
D
P
K
D
K
Chimpanzee
Pan troglodytes
XP_001167352
301
34100
S87
A
P
L
T
Q
N
Q
S
H
D
D
P
K
D
K
Rhesus Macaque
Macaca mulatta
XP_001116496
301
34160
S87
A
P
L
T
Q
N
Q
S
H
D
D
P
K
D
K
Dog
Lupus familis
XP_849422
247
28132
L62
L
L
V
E
L
S
P
L
F
P
D
T
L
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z120
268
30585
K66
D
P
K
D
E
K
E
K
H
S
G
A
Q
V
E
Rat
Rattus norvegicus
XP_001054797
267
30550
K65
D
P
K
D
E
K
E
K
H
S
G
A
Q
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516298
226
25512
G49
D
I
G
C
G
Y
G
G
L
L
V
E
L
S
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NU94
273
31824
A64
K
P
L
V
P
D
C
A
H
D
D
A
K
D
L
Zebra Danio
Brachydanio rerio
Q5XJ57
241
27917
C62
V
E
F
A
D
I
G
C
G
Y
G
G
L
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O77263
256
29406
M63
E
D
V
D
W
R
S
M
Y
P
G
I
Q
Q
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23126
256
30022
Y62
W
T
K
Y
Y
G
D
Y
T
K
G
R
Q
V
D
Sea Urchin
Strong. purpuratus
XP_790960
406
47124
Q128
V
R
S
Q
L
L
S
Q
T
Y
L
T
Q
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
B6SHG7
255
29101
E62
D
K
G
S
D
G
E
E
A
A
A
P
Q
Q
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GXB7
251
28800
K63
E
A
D
N
K
F
I
K
K
V
E
F
A
D
I
Baker's Yeast
Sacchar. cerevisiae
Q12009
286
33373
Y69
F
S
D
H
Q
L
E
Y
P
V
S
P
Q
D
M
Red Bread Mold
Neurospora crassa
Q7RZC1
293
33715
K73
V
E
E
P
I
E
Q
K
T
E
T
T
E
S
E
Conservation
Percent
Protein Identity:
100
90.6
90.6
81.5
N.A.
88
88.4
N.A.
64.8
N.A.
69.5
67.7
N.A.
47.4
N.A.
50.7
42.3
Protein Similarity:
100
91.3
91
83.6
N.A.
92.3
90.9
N.A.
72
N.A.
80
76.4
N.A.
59.7
N.A.
64.8
51.2
P-Site Identity:
100
100
100
6.6
N.A.
13.3
13.3
N.A.
0
N.A.
46.6
0
N.A.
0
N.A.
0
0
P-Site Similarity:
100
100
100
20
N.A.
40
40
N.A.
0
N.A.
60
0
N.A.
20
N.A.
6.6
13.3
Percent
Protein Identity:
N.A.
52.5
N.A.
50
46.8
48.8
Protein Similarity:
N.A.
68.4
N.A.
68.4
61.5
66.2
P-Site Identity:
N.A.
6.6
N.A.
6.6
20
6.6
P-Site Similarity:
N.A.
26.6
N.A.
20
33.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
7
0
7
0
0
0
7
7
7
7
19
7
0
0
% A
% Cys:
0
0
0
7
0
0
7
7
0
0
0
0
0
0
0
% C
% Asp:
25
7
13
19
13
7
7
0
0
25
32
0
0
38
7
% D
% Glu:
13
13
7
7
13
7
25
7
0
7
7
7
7
0
19
% E
% Phe:
7
0
7
0
0
7
0
0
7
0
0
7
0
0
0
% F
% Gly:
0
0
13
0
7
13
13
7
7
0
32
7
0
0
7
% G
% His:
0
0
0
7
0
0
0
0
38
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
7
7
7
0
0
0
0
7
0
7
13
% I
% Lys:
7
7
19
0
7
13
0
25
7
7
0
0
25
0
19
% K
% Leu:
7
7
25
0
13
13
0
7
7
7
7
0
19
7
13
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
7
0
19
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
38
0
7
7
0
7
0
7
13
0
32
0
0
7
% P
% Gln:
0
0
0
7
25
0
25
7
0
0
0
0
44
13
0
% Q
% Arg:
0
7
0
0
0
7
0
0
0
0
0
7
0
0
7
% R
% Ser:
0
7
7
7
0
7
13
19
0
13
7
0
0
19
0
% S
% Thr:
0
7
0
19
0
0
0
0
19
0
7
19
0
0
0
% T
% Val:
19
0
13
7
0
0
0
0
0
13
7
0
0
19
7
% V
% Trp:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
7
7
0
13
7
13
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _